Sun Yat-sen Physics National Demonstration Center engaged in scientific research and teaching equipment about weak signal detection for more than 10 years, launched a series of weak signal detection instruments for scientific research and experimental teaching, and applied for dozens of patents. The OE1022 facing to scientific research has excellent performance on stability, convergence speed and measurement, and has been widely used and recognized in hundreds of scientific research institutes in home and abroad. In recent years, it has won the first prize of "10 years Symposium of Achievements Exhibition of National Experimental Teaching Demonstration Center of Colleges and Universities" and the first prize of "2016 Homemade Instrument for Physics Experimental Teaching in Colleges and Universities of China". The center launched the teaching lock-in amplifier OE1022E and the weak signal detection teaching experiment box OE5001, which can effectively cultivate students with non-electronic background such as physics, chemistry and biology to grasp the modern technical means of weak signal detection and deeply understand the principle of weak signal detection .